Categories
General Materials Research Medicinal Science

Nanobiotechnology and Biomaterials in Nuclear Medicine – special issue

Nuclear Medicine, a medical specialty involving the application of radioactive substances and magnetic materials in the diagnosis and treatment of disease have been highly successful in diagnosis of difficult to detect diseases and therapy of various dreaded diseases. Recently, there have been a tremendous research progress in development of newer methods, conjugates and pharmaceuticals for diagnosis and therapy using nanomaterials and nanomedicine approaches in radioactive materials.

The purpose of this special issue proposal is to summarize the recent advances in the field of new NanoMedicinal and Nanobiotechnological advances in development of probes and materials for potential molecular targets and understanding of their mechanism of actions, new radioconjugates development using nanobiomaterials, clinical evaluation and application of new Nano-radiopharmaceuticals, and new techniques/therapy development using Biomaterials. Recent progress will be covered through research articles, review articles and short communications.

The subtopics to be covered in this issue are (though not limited to):

NanoChemistry of new radioactive elements.
– Organic chemistry of Nano-radiopharmaceuticals, chelating agents and standalone Nano-radiopharmaceuticals.
– Progress in SPECT using Nanobiomaterials.
– Progress in Nano-Positron Emission Tomography (nanoPET).
– Application of nanoscience and nanotechnology to Nuclear Medicine.
– Identification of new therapeutic targets.
– Treatment advances of various diseases – cancer, infections, inflammations etc using nano-radiopharmaceuticals.
– Clinical studies and evaluation of nano-radiopharmaceuticals.
– Malarial/mycobacterial/microbial/viral diagnosis and therapy development using nano(bio)materials including biochemical aspects of nano-biomaterials.
– Therapeutic and diagnostic applications of new nano and biomaterials.
– New therapeutic policies and emerging targets for Nuclear nanoMedicine.
– New approaches adopted for the development of nanomedicine of new radiodiagnostic and radiotherapeutic molecules.
– Rational design and drug discovery-Structure-activity relationship (SAR).
NanoDrug Delivery of radiopharmaceuticals – application of different nanobiotechnology conjugates and systems in radiopharmaceuticals.
– Synthetic strategies of new radioactive conjugate molecules.
– Molecular self-assembly as drug delivery carriers of radiopharmaceuticals – Nanotechnology and Biotechnology.
– Environmental aspects, safety measures advances in nuclear medicine.

Provisional Schedule:

Manuscript submission: Submission open and ongoing now.
Issue Completion: October 2020.

Editors:

Dr. Anil Mishra
Dr. Anil Kumar Mishra
Scientist ‘G’ and Add Director,
Institute of Nuclear Medicine and Allied Science,
DRDO, Timarpur, Delhi. India
Dr. B.S. Chhikara,
University of Delhi
email: drbs @ aditi. du.ac.in

Nuclear and Nano-Medicine researchers are invited to submit their research / review article for this special issue. Manuscript should be prepared and submitted as per author guidelines provided on journal site.

Important Links:

Author Guidelines for preparation of manuscript:

Manuscript template (download): Download template MS word 2007-2010, Citation manager style files and other details are provided in author guidelines section on journal site.

http://thesciencein.org/author-guidelines-for-journal-of-nanomedicine section -nanomaterials-materials-nanoscience/

Manuscript Submission: Authors need to submit their manuscript on http://thesciencein.org/journal/index.php/jmns/about/submissions OR http://pubs.iscience.in/journal/index.php/cbl/about/submissions (India-regional site).

There is no fees for publication in special issue or journal.

Categories
Articles Medicinal Science

Curcumin loaded Silica Nanoparticles and their therapeutic applications: A review

Curcumin loaded Silica Nanoparticles and their therapeutic applications: A review

urn:nbn:sciencein.jmns.2020.v7.99

Published in Journal of Materials NanoScience

  • Parul Pant University of Delhi
  • Dr. Chetna Gupta University of Delhi
  • Sagar Kumar Indian Institute of Science
  • Apoorva Grewal University of Delhi
  • Shivani Garg University of Delhi
  • Aishwarya Rai University of Delhi

Keywords: Silica, Nanoparticles, trumeric, drug delivery, cancer, diabetes, nanomedicine, biomedical science

Abstract

Silica nanoparticles offer a promising platform for the delivery of drugs, in particular for the drugs which lack water solubility, target capability and have non-specific distribution, systematic toxicity and low therapeutic index. In this review, we focus on the synthesis and therapeutic (particularly, anti-cancer) applications of Curcumin loaded Silica Nanoparticles. Various surface modifications of silica nanoparticles have been discussed that are used to enhance their therapeutic applications. The characterization techniques and study of their biocompatibility have also been presented.

Cite as: Pant, P., Gupta , C., Kumar, S., Grewal, A., Garg, S., & Rai, A. (2020). Curcumin loaded Silica Nanoparticles and their therapeutic applications: A review. Journal of Materials NanoScience, 7(1), 1-18.

Full text at http://thesciencein.org/journal/index.php/jmns/article/view/99 and http://www.pubs.iscience.in/journal/index.php/jmns/article/view/989

Categories
Journals Materials Research Medicinal Science

Drug delivery with nano-materials – significance and advances in Medicinal Chemistry

The development and evaluation of new drug delivery systems (particularly with nanoscale materials) has been potentiating the advances in drug development. This special issue is meant to cover recent advances in development and application of nano delivery systems, peptide based delivery systems, self assembly of peptides structures and similar natural systems, Gene delivery, lipids, liposomes, miscelle, nanoparticular and carbon nanomaterials in drug delivery, mechanistic understanding of delivery systems, and other development of nanomaterials for drug delivery in medicinal chemistry.

Issue Editors:

Prof. Keykavous Parang
Associate Dean of Research, Graduate Studies, and Global Affairs
Professor of Medicinal Chemistry and Pharmacology
Harry and Diane Rinker Health Science Campus
9401 Jeronimo Rd. Irvine, CA 92618-1908. USA
Dindyal Mandal
Senior Research Associate
Harry and Diane Rinker Health Science Campus
9401 Jeronimo Rd. Irvine, CA 92618-1908. USA
Dr. B.S. Chhikara
Department of Chemistry,
University of Delhi, Aditi Mahavidyalaya,
Delhi 39. India

Submission

Article (Research articles and Review Articles) should be submitted online on the journal site http://www.thesciencein.org/journal/index.php/jmns as per author guidelines. Authors need to indicate submission to special issue in cover letter to editor.

Authors may also forward their final manuscript to editors via email ( bschhikara (at) gmail [dot] com )

Submission Deadline Submission ongoing, issue completion by May 2020

There is no publication charges for publishing in special issue.

Articles

Critical evaluation of pharmaceutical rational design of Nano-Delivery systems for Doxorubicin in Cancer therapy
Running Title: Rationale of designing of nanoparticular delivery systems and impact of chemistry used with doxorubicin for anti-cancer therapy
Bhupender S. Chhikara, Brijesh Rathi, Keykavous Parang

Synthesis, Characterization, Biocompatibility of Curcumin loaded Silica NP’s & their Therapeutic Applications: A Review
Parul Pant, Chetna Gupta, Sagar Kumar, Apoorva Grewal, Shivani Garg, Aishwarya Rai

Current advances in drug delivery systems for treatment of Triple negative breast cancer (TNBC
Pooja Mittal, Sujata Singh, Archana Singh, Indrakant Kumar Singh

Categories
Articles

Critical evaluation of pharmaceutical rational design of Nano-Delivery systems for Doxorubicin in Cancer therapy

Critical evaluation of pharmaceutical rational design of Nano-Delivery systems for Doxorubicin in Cancer therapy

Published in: Journal of Materials NanoScience

urn:nbn:sciencein.jmns.2019v6.95

Running title: Rationale of designing of nanoparticular delivery systems and impact of chemistry used with doxorubicin for anti-cancer therapy

  • Bhupender S. Chhikara University of Delhi
  • Brijesh Rathi University of Delhi
  • Keykavous Parang Chapman University

Keywords: Adriamycin, Cancer Drug, CPP, Drug Delivery System, Lipophilic Dox, TAT peptide

Abstract

Doxorubicin (Dox), an antineoplastic drug, has been extensively used for the treatment of different cancers. Dox is hydrophilic and therefore distributes to normal organs at a faster rate. Due to its required high doses, it poses severe toxicity, such as cardiotoxicity and nephrotoxicity. Diverse approaches, including nanoparticulate delivery systems, have been designed and evaluated to improve its delivery to the target site and reduce toxicity to normal organs; however, this has met little success. Here in this review, we have discussed various systems (metal nanoparticles, carbon nanotubes, fullerenes, liposomes, dendrimers, cyclic peptides, and other covalent/non-covalent systems) that have been used for Dox. We have critically evaluated their designing and outcome (in vitro and in vivo) with potential applications in the clinical setting.

Cite as: Chhikara, B., Rathi, B., & Parang, K. (2019). Critical evaluation of pharmaceutical rational design of Nano-Delivery systems for Doxorubicin in Cancer therapy. Journal of Materials NanoScience, 6(2), 47-66.

Retrieved full text from http://pubs.thesciencein.org/journal/index.php/jmns/article/view/95