Journal of Materials NanoScience 2020-08-03T02:26:18+00:00 Editorial, J Material NanoScience Open Journal Systems <p>The Journal of Material NanoScience is an international peer-reviewed journal for publcation of research in the field of Materials Sciences, Materials Chemistry, Functional Materials, NanoScience, Nanobiotechnology, Biomaterials, Physics and Engineering of Materials.</p> Role of polarized tip-enhanced Raman spectroscopy in the enhancement of interface optical phonon modes in AlGaN multi-quantum wells 2020-08-03T02:26:18+00:00 A.K. Sivadasan Prajit Dhara Chirantan Singha Raktima Basu Santanu Parida A. Bhattacharyya Kishore K. Madapu Sandip Dhara <p>Group III nitride based two-dimensional multi-quantum well (MQW) nanostructures find remarkable applications in the visible to ultraviolet light sources. The interface optical (IFO) phonon modes in a <em>c</em>-axis oriented superlattice of [Al<sub>0.35</sub>Ga<sub>0.65</sub>N (~1.75 nm)/Al<sub>0.55</sub>Ga<sub>0.45</sub>N (~2nm)]<sub>20 </sub>MQWs are observed using tip-enhanced Raman spectroscopic (TERS) studies. The near-field studies using TERS probe with an Au spherical nanoparticle of ~ 200 nm&nbsp;diameter were carried out at ambient conditions showing approximately two to three orders of enhancement in the Raman intensities.&nbsp; The interface phonon mode belonging to <em>E</em><sub>1</sub> symmetry [IFO(<em>E</em><sub>1</sub>)] vibrating normal to the <em>c</em>-axis of MQWs appeared to be more prominent in the case of TERS measurement compared to that for the other interface phonon mode of <em>A</em><sub>1</sub> symmetry. The confined electric field of the polarized electro-magnetic excitation using TERS probe, parallel to the plane of the interface of MQW, is made responsible for the plasmonic enhancement of IFO(<em>E</em><sub>1</sub>) phonon mode. The confinement was verified using finite-difference time-domain simulation.</p> 2020-01-02T00:00:00+00:00 Copyright (c) 2020 ScienceIn Publishing Synthesis of blue light emitting 5-carboxylicacid-2-arylsubstituted benzimidazoles as photosensitizers for dye-sensitized solar cells 2020-08-03T02:26:16+00:00 T.V.B. Nagaveni K.M. Mahadevan Ravikumar Naik T.O. Shrungesh Kumara <p>A series of 5-Carboxylic Acid-2-Aryl substituted Benzimidazoles <strong>3a-c</strong>, were synthesized and their Photo- physical, Electrochemical and DSSCs performance were studied. The UV-vis absorption and Photoluminescence (PL) Spectra of the compounds <strong>3b</strong> and <strong>3c</strong> exhibited intense deep-blue emissions with PL maximum at around 380, 382 and 400 nm (Fig. 3). Incidentally, their PL quantum yields (?f) in solutions were found to be 0.36, 041 and 0.46 respectively. Thus, their emission spectrum displayed a broad FWHM feature extending to a longer-wavelength region, promoting the <em>y </em>value of the CIE resulting in a sky-blue emission of the Dyes <strong>3a-c</strong>. Further, the good thermal stability and small FWHMs of the dyes <strong>3a-c</strong> indicates as promising compounds for deep-blue emitters in OLEDs. The Photovoltaic performances of the Solar Cells fabricated from the prepared Electrodes under AM1.5 Solar irradiation (85&nbsp;mW/cm<sup>2</sup>) are shown in Fig.&nbsp;6. The Short-circuit Current Density (<em>J</em><sub>SC</sub>), Open-circuit Voltage (<em>V</em><sub>OC</sub>), Fill Factor (FF) and overall Conversion Efficiency (<em>?</em>) clearly reveals that the Dye <strong>3c</strong> shows higher efficiency (2.87 %) contributed by high value of <em>J</em><sub>SC</sub>, <em>V</em><sub>OC</sub> and FF.</p> 2020-06-25T00:00:00+00:00 Copyright (c) 2020 ScienceIn Publishing Curcumin loaded Silica Nanoparticles and their therapeutic applications: A review 2020-08-03T02:26:17+00:00 Parul Pant Chetna Gupta Sagar Kumar Apoorva Grewal Shivani Garg Aishwarya Rai <p>Silica nanoparticles offer a promising platform for the delivery of drugs, in particular for the drugs which lack water solubility, target capability and have non-specific distribution, systematic toxicity and low therapeutic index. In this review, we focus on the synthesis and therapeutic (particularly, anti-cancer) applications of Curcumin loaded Silica Nanoparticles. Various surface modifications of silica nanoparticles have been discussed that are used to enhance their therapeutic applications. The characterization techniques and study of their biocompatibility have also been presented.</p> 2020-01-06T00:00:00+00:00 Copyright (c) 2020 ScienceIn Publishing Doxorubicin-loaded magnetic nanoparticles downregulate expression of anti-apoptotic genes in resistant breast cancer cells 2020-08-03T02:26:14+00:00 Serap YAlcin Pelin Mutlu Gozde Unsoy Rouhollah Khodadust Ufuk Gunduz <p>In this research, surface of magnetic nanoparticles (IO-NPs) were coated with dextran polymer (Dex-IO-NPs) in which dextran provides both cavities for drug loading and drug stability. Dex-IO-NPs were synthesized by co-precipitation of iron salts with ammonium hydroxide in the presence of dextran solution. Dex-IO-NPs were then characterized by FTIR, TGA, TEM, SEM and VSM analyses. Doxorubicin was loaded on Dex-IO-NPs (Dox-Dex-IO-NPs) and applied to breast cancer (MCF-7) and Doxorubicin resistant (MCF-7/1000nM-Dox) breast cancer cell lines. Dex-IO-NPs were highly internalized and localized within the cells. Importantly, the half-maximal inhibitory concentrations (IC<sub>50</sub>) of Dox-Dex-IO-NPs were 0.8 µM and 25 µM in MCF-7 and MCF-7/1000nMDox cells respectively, which were 2 and 7 times more effective in cell death with respect to free Doxorubicin. The release of anti-cancer agent from Dox-Dex-IO-NPs occurs with natural degradation of Dextran, and allows nuclear uptake of Doxorubicin, which results an increase in the ef?cacy of Doxorubicin. The anti-apoptotic genes were downregulated in Dox-Dex-IO-NPs treated cells as compared to free Doxorubicin treated cells, revealing the higher cytotoxicity and apoptotic potential of Dox-Dex-IO-NPs. These results may imply that Dex-IO-NPs particles can have a potential to be an efficient tool for drug delivery in breast cancer therapy.</p> 2020-06-22T00:00:00+00:00 Copyright (c) 2020 ScienceIn Publishing